Since the late 1990s Patricia Clarkson has been one of the darlings of independent film.

First coming on the scene in 1987 when she portrayed Eliot Ness' wife in 'The Untouchables,' Clarkson found notice with indie film fans 11 years later when she starred as an aging, drug-addicted German model in Lisa Cholodenko's debut feature, 'High Art.'

In 2003 Clarkson performed the unprecedented feat of starring in four(!) films at the Sundance Film Festival, including 'All the Real Girls,' 'The Station Agent,' 'The Baroness and the Pig' and 'Pieces of April,' for which she received a Best Supporting Actress Oscar nomination for playing a mother dying of cancer. She also gained attention on the small screen with her role as Sarah O'Connor in 'Six Feet Under.'

More recently she co-starred in 'Vicky Cristina Barcelona,' 'Whatever Works' and 'Shutter Island.' But perhaps the biggest sign of her progression as a star was her inclusion last year in Andy Samberg's Saturday Night Live short 'Motherlover,' along with Justin Timberlake and Susan Sarandon.

Now Clarkson will finally be carrying a film, as she plays the lead role in Ruba Nadda's love story, 'Cairo Time.'