Five years after appearing together in the Oscar-winning drama 'Brokeback Mountain,' Jake Gyllenhaal and Anne Hathaway have reunited for the sexy new romantic comedy 'Love and Other Drugs.'

Gyllenhaal plays Jamie Randall, a smooth-talking pharmaceutical rep who falls for an equally charming Maggie (Hathaway) while stationed in Ohio. Their relationship begins casually -- with tons of nudity, no less -- then takes a serious turn when it's revealed that Maggie has Parkinson's disease.