The cast of 'How Do You Know' sure is packed with A-List stars; it features everyone Owen Wilson to Paul Rudd to Reese Witherspoon.

The movie, in theaters this Friday, is about Lisa, a young woman (Witherspoon) who must choose between two men -- the charismatic but clueless Matty (Wilson) and the charming but flustered (George). The only catch: Lisa and George meet under the worst of circumstances, a premise that director James L. Brooks says was the inspiration for the film.

Moviefone talked to the three stars of the movie, along with actress Kathryn Hahn and director Brooks, last week about love, bad first impressions, dating faux and the ultimate question: How do you know?