With a starring role in 'The Dark Knight Rises' and four more top billings coming up in the next year alone, we're gonna call it: By the time 2013 rolls around, Joseph-Gordon Levitt will have taken over the world.

Up next on the roster for JGL is '50/50', a dramedy about a young man (Levitt) who discovers that he has cancer and tries to beat it with the help of his best friend (Rogen). Directed by Jonathan Levine ('The Wackness'), loosely based on the real-life experiences of screenwriter Will Reiser and co-starring Anna Kendrick, Bryce Dallas Howard and Anjelica Huston, '50/50' is set to release on Sept. 30 from Summit Entertainment.

Hit the jump for the trailer.