Awards
| Year | Award | Category | Movie | Result |
|---|---|---|---|---|
| 2010 | Golden Globes | Best Performance by an Actress in a Motion Picture - Musical or Comedy | The Tourist (2010) | Nominated |
| 2008 | Academy Awards | Best Actress | Changeling (2008) | Nominated |
| 2008 | British Academy of Film and Television Arts | Best Actress | Changeling (2008) | Nominated |
| 2008 | Broadcast Film Critics Association | Best Actress | Changeling (2008) | Nominated |
| 2008 | Chicago Film Critics Association | Best Actress | Changeling (2008) | Nominated |
| 2008 | Golden Globes | Best Performance by an Actress in a Motion Picture - Drama | Changeling (2008) | Nominated |
| 2008 | London Film Critics Association | Best Actress | Changeling (2008) | Nominated |
| 2008 | Screen Actors Guild | Best Actress | Changeling (2008) | Nominated |
| 2007 | Broadcast Film Critics Association | Best Actress | A Mighty Heart | Nominated |
| 2007 | Chicago Film Critics Association | Best Actress | A Mighty Heart | Nominated |
| 2007 | Golden Satellite Award | Best Performance by an Actress in a Motion Picture - Drama | A Mighty Heart | Nominated |
| 2007 | Golden Globes | Best Performance by an Actress in a Motion Picture - Drama | A Mighty Heart | Nominated |
| 2007 | Independent Spirit Awards | Best Female Lead | A Mighty Heart | Nominated |
| 2007 | Screen Actors Guild | Best Actress | A Mighty Heart | Nominated |
| 1999 | Academy Awards | Best Supporting Actress | Girl, Interrupted | Won |
| 1999 | Broadcast Film Critics Association | Best Supporting Actress | Girl, Interrupted | Won |
| 1999 | Golden Globes | Best Supporting Actress in a Series, Miniseries or Motion Picture Made for Television | Girl, Interrupted | Won |
| 1999 | Screen Actors Guild | Best Female Actor in a Supporting Role | Girl, Interrupted | Won |
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