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American character actor Douglas Henderson shifted his activities from stage to screen in 1952, when he appeared in Stanley Kramer's Eight Iron Men. Like many general purpose actors of the era, he was frequently cast in science fiction and horror films along the lines of King Dinosaur and Invasion of the Saucer Men. He was generally cast in authoritative or military roles: officers, congressmen, FBI agents, and the like. Douglas Henderson's final film assignment was the 1970 thriller Zigzag; eight years later, he committed suicide via carbon monoxide poisoning.

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