The daughter of a stage actress, Helen Parrish began appearing in silent films as a child. In the early '30s, she was briefly a member of Hal Roach's Our Gang. Parrish went on to inspire hisses as Deanna Durbin's spiteful nemesis in such films as Three Smart Girls Grow Up (1939) and First Love (1939). She began playing adult roles at Universal and RKO in 1940 before her career went into a slow decline at Monogram. For many years the wife of People Are Funny and You Bet Your Life producer John Guedel, Helen Parrish died of cancer at the age of 34. Her older brother was juvenile star-turned-editor-turned-director Robert Parrish.