Lab assistant Igor (John Cusack) dreams of becoming a mad scientist like his master, Dr. Glickenstein. When the doctor runs afoul of his own invention, Igor seizes the chance. With the help of his friends Scamper (Steve Buscemi) and Brain (Sean Hayes), Igor plans to win the kingdom's annual science fair by building the most-evil monster ever. The problem is that Eve (Molly Shannon), as the monster is called, is sweeter than sugar and would rather be an actress.
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