Keane (Damian Lewis) is a mentally unbalanced man who roams the Port Authority Bus Terminal in New York City, looking for his daughter, who was supposedly kidnapped a year earlier. When he's not at the bus station he holes up in a dingy hotel, numbing himself with drugs and alcohol. But when Lynn (Amy Ryan), a young single mother, and her daughter, Kira (Abigail Breslin), check into the hotel, Keane reaches out to help them, and he ends up helping himself at the same time.
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