I know this sounds like some sort of Elvis' Death Day joke, but I'm here to tell you that it's not. Samuel L. Jackson is starring in a movie called Snakes on a Plane in which, you guessed it, he shares airspace with a whole mess of snakes-- 500 of them, to be precise. It's all part of a plan (the snakes, not the movie) by an assassin, you see.
The assassin has been hired to kill someone in witness protection, and somehow knows what plane his target is on (Sam is the FBI agent in charge of transferring the witness). So he sneaks a crate of 500 poisonous snakes onto the plane. Seems logical. When the plane is over the Pacific Ocean, the crate opens and all hell breaks loose. From then on, Jackson says, "it's us battling snakes to LA." Sweet. The movie's title was briefly changed to Flight 121, presumably to disguise the fact that it's a movie about snakes on a plane, but ultimately the producers decided it was best to call a spade and spade and changed it back. Again, this is not a joke.
So, let me get this straight. You're going to take one of the primal battles of nature-- Man v Snake-- and then mix in both air travel and Sam Jackson? Holy cow. I don't know about anyone else, but this thing just leaped to the top of my Can't Bloody Wait list.