While the premise is certainly intriguing, I'm getting kind of tired of that whole "guy wakes up in a strange place and doesn't remember anything" storyline. The most recent film to apply this premise was Unknown, and that flick was a prime example of why this is a risky set-up. Basically, it all comes down to the script. Anyone can come up with some bizarre situation to throw their main character in, but if the script gets lazy (and the writer gets afraid), then the film just won't work. Memento worked because the Nolan brothers were sticklers for details, and made sure every piece of that film serviced the plot and moved things forward. Unfortunately, Unknown was so focused on the surprise twists that it botched the details, as well as the characters, leaving us a fantastic set-up with nowhere to go but downhill.
Now, Nala Films is apparently confident that writers Eddie and Chris Borey got things right, and have launched development of their script, Open Grave, with plans to begin shooting next year. Here we go again -- the plot revolves around some dude who wakes up in the middle of the woods in a pit full of dead bodies with no idea who these people are, how they were killed and whether or not he was the one who caused their death. Sure, it sounds like a great set-up -- but what about the rest of the script? I have no idea who the Borey brothers are and there's a good chance this is their first produced script. That's unsettling, however Nolan was fairly new to the game when he wrote Memento -- so you never can tell. No word yet on a cast or director; we'll let you know if any more details pop up.