Set in futuristic Metro City, 'Astro Boy' (based on the Japanese manga comic) is about a young robot with incredible powers, created by a scientist named Tenma (Nicolas Cage). Powered by positive "blue" energy, Astro Boy (Freddie Highmore) is endowed with super strength, x-ray vision, unbelievable speed and the ability to fly.

Embarking on a journey in search of acceptance, Astro Boy encounters many other colourful characters along the way. Through his adventures, he learns the joys and emotions of being human, and gains the strength to embrace his destiny. Ultimately learning his friends and family are in danger, Astro Boy marshals his super powers and returns to Metro City in a valiant effort to save everything he cares about.