In 'Love and Other Drugs,'Jake Gyllenhaal
and Anne Hathaway
play opposites who attract and then undress one another with pretty steamy frequency. It's a stark departure from their previous onscreen coupling, in 'Brokeback Mountain,'
in which the pair first gets busy in the backseat of a car, before dwindling into a loveless marriage.
How does Jake and Anne's romantic reunion stack up compared to other leading men and ladies who've taken a second shot (or shot a second take) at love, Hollywood-style? We're not talking about when characters stay together for the sake of the sequel, but when two movie icons double down on their onscreen chemistry in completely new roles. Here's nine more of them, with our take on which films sizzle or fizzle.
Los Angeles police officer Jack (Keanu Reeves) angers retired bomb squad member Howard Payne (Dennis... Read More
On his way to Vienna, American Jesse (Ethan Hawke) meets Celine (Julie Delpy), a student returning to... Read More
Through a life of hard work, airline owner Tom Mullen (Mel Gibson) has amassed a great deal of wealth.... Read More
James Cameron's "Titanic" is an epic, action-packed romance set against the ill-fated maiden voyage of... Read More
Having already left three grooms at the altar, Maggie Carpenter (Julia Roberts) is branded "the runaway... Read More
Lethal Weapon 3
Veteran police detective Roger Murtaugh (Danny Glover) is only days away from retiring when he and his... Read More
50 First Dates
Playboy vet Henry sets his heart on romancing Lucy, but she has short-term memory loss; she can't remember... Read More
A sequel to "Before Sunrise," this film starts nine years later as Jesse (Ethan Hawke) travels across... Read More
The Lake House
A lonely doctor (Sandra Bullock), who once lived in a beautiful lakeside home, falls in love via letters... Read More
Treasure hunter Ben "Finn" Finnegan (Matthew McConaughey) has sunk his marriage to Tess (Kate Hudson)... Read More
Jamie Rowan (Katharine Hepburn) is a widow who decides to do her patriotic duty by marrying military... Read More
Woman of the Year
Tess Harding (Katharine Hepburn) is a progressively-minded political journalist. Sam Craig (Spencer Tracy)... Read More