Nurse JackieRIP "Nurse Jackie." Time of death: 3:30 p.m., Sept. 10, 2014.

Showtime announced it is canceling the acclaimed comedy starring Edie Falco after its seventh season, which begins filming this week.

"Edie is one of our finest actresses. We are so honored to have had her on the network. She creates indelible characters and Nurse Jackie Peyton is no exception," said Showtime President David Nevins in a statement.

"I know this final season will bring her story to a close that will satisfy the ever-growing number of loyal viewers who have been entranced and, at times, appalled by Jackie through the years. I want to thank Edie, the incredible cast of Nurse Jackie and Clyde Phillips and Richie Jackson who have led the show to the success that it is today."

"Nurse Jackie" debuted in 2009 and in six seasons, racked up numerous Emmy and Golden Globe nominations. Falco and co-star Merritt Wever both took home Emmy trophies (former "Sopranos" star Falco is the only woman ever to win the lead actress awards in the drama and comedy categories).

The final season will feature some changes to the the show, as Peter Facinelli moves to recurring status and "Monk" star Tony Shalhoub joins the cast as a new doctor.

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