Talk about a (big) sick duo: Kumanil Nanjiani and Issa Rae are pairing up to star in a romantic comedy titled "The Lovebirds."

According to The Hollywood Reporter, the project will reunite Nanjiani and his "Big Sick" director Michael Showalter. The actor earned an Oscar nomination for Best Original Screenplay for the 2017 comedy, alongside his wife Emily Gordon.

Nanjiani and Rae are both HBO comedic stars — he appears on "Silicon Valley," she created and stars in "Insecure."

In "The Lovebirds," they'll play a couple on the brink of a break-up. But before they can split, they become embroiled in a bizarre and hijinks-filled murder mystery. As they work to clear their names and solve the case, the couple needs to figure out how they, and their relationship, can survive the night.

Nanjiani can next be seen on the big screen in this summer's "Stuber" opposite Dave Bautista, while Rae stars in "Little" this April.