Ice Bound: A Woman's Survival at the South Pole (2003)

In this adaptation of a true story, Ohio physician Dr. Jerri Nielsen (Susan Sarandon) is stranded at a research station in Antarctica. Nielsen keeps her distance from the other researchers, until she finds a growth in her breast and shares her concerns about it with Big John Penny (Aidan Devine) and Claire Furinski (Cynthia Mace). After discovering that the lump is cancerous, Nielsen creates her own method of chemotherapy and fights to survive the deadly winter.