Unwanted guests can drive anyone batty — as it does, and much more, to Jennifer Lawrence in the new trailer for Darren Aronofsky's new film, "mother!"

The plot of the movie is unclear from the trailer, but it involves a husband (Javier Bardem) and wife (Lawrence) and strange, uninvited houseguests (Ed Harris, Michelle Pfeiffer). Eerie events start to unfold, and Lawrence grows increasingly unhinged.

"All I'm trying to do is bring life into this house!" Bardem shouts at one point. "Open the door to new people, new ideas."

Aronofsky certainly knows how to stoke tensions and play with emotions in psychological thrillers like "Black Swan" and "Requiem for a Dream." "mother!" looks more like an outright horror flick, with some very creepy imagery — a shot of a group of people with lanterns on the lawn, and at one point, it looks like the couple's house gets dilapidated in a matter of moments.

"mother!" also stars Domhnall Gleeson, Brian Gleeson, and Kristen Wiig, and will premiere at the Venice Film Festival. It opens in theaters September 15.