The cartels had better watch their backs.

In the first trailer for "Sicario 2: Soldado," CIA agent Matt Graver (Josh Brolin) and partner Alejandro (Benicio del Toro) are ready to take their war on drugs to the next level. In the first movie, Emily Blunt starred as an FBI agent who joins a task force to take down the leaders of a cartel.

But now, the cartels are trafficking terrorists across the border, so Graver's bosses let him completely loose — no rules this time. "You're going to help me start a war," he tells Alejandro.

"With who?" Alejandro wonders.

"Everyone."

As the first movie revealed, Alejandro is out for revenge for the deaths of his family. But things are more complicated when this new assignment brings him into the orbit of the daughter of a drug lord (Isabella Moner). He comes to the point where he "either has to follow orders or make the right decision and so that's kind of where the character's stuck," del Toro explained to Entertainment Weekly.

"Sicario 2: Soldado" opens in theaters June 29.