"This Is Us" may have just ended its second season but don't put away the tissue box yet. That show's creator, Dan Fogelman, wrote and directed a new movie called "Life Itself" that looks just as heart-tugging and tear-jerking.



Amazon Studios debuted the first teaser trailer for "Life Itself," which centers on a couple (Olivia Wilde and Oscar Isaac) course of several decades. It's a globe-hopping, multi-generational story that is as emotional and sweeping as "This Is Us" fans expect from a Fogelman project.



There's a single event that ties together the entire story. As Isaac muses, "It's strange think about, how a completely random moment had shaped my entire life."





The movie is a star-studded affair featuring Annette Bening, Antonio Banderas, Mandy Patinkin, Olivia Cooke, and Laia Costa. This is Fogelman's second directorial effort after 2015's "Danny Collins." As a writer, he's worked on the first two "Cars" movies, "Tangled," "Bolt," and his breakout, "Crazy Stupid Love." On the television side, of course, he's well-known for making everyone cry with "This Is Us."



"Life Itself" opens in theaters September 21