"This Is Us" may have just ended its second season but don't put away the tissue box yet. That show's creator, Dan Fogelman, wrote and directed a new movie called "Life Itself" that looks just as heart-tugging and tear-jerking.

Amazon Studios debuted the first teaser trailer for "Life Itself," which centers on a couple (Olivia Wilde and Oscar Isaac) course of several decades. It's a globe-hopping, multi-generational story that is as emotional and sweeping as "This Is Us" fans expect from a Fogelman project.

There's a single event that ties together the entire story. As Isaac muses, "It's strange think about, how a completely random moment had shaped my entire life."

The movie is a star-studded affair featuring Annette Bening, Antonio Banderas, Mandy Patinkin, Olivia Cooke, and Laia Costa. This is Fogelman's second directorial effort after 2015's "Danny Collins." As a writer, he's worked on the first two "Cars" movies, "Tangled," "Bolt," and his breakout, "Crazy Stupid Love." On the television side, of course, he's well-known for making everyone cry with "This Is Us."

"Life Itself" opens in theaters September 21

Life Itself Movie Poster
Life Itself
In Theaters on September 21, 2018

The lives of people from New York to Spain intersect over the course of different generations. Read More