'The Twisted Tale of Amanda Knox' Exclusive Interview

Moviefone speaks with Grace Van Patten about 'The Twisted Tale of Amanda Knox'. "I'm curious to see how people react," she said about the limited series.

Premiering August 20th on Hulu is the new limited series ‘The Twisted Tale of Amanda Knox’, which is based on the true story Amanda Knox, an American wrongly convicted of murder in Italy in 2007.

The Twisted Tale of Amanda Knox

"Does the truth exist if no one believes it?"

Drama

Audience
Score

Air Date: August 20th, 2025

Networks: Hulu

Starring: Grace Van Patten, Sharon Horgan, Francesco Acquaroli

Watch The Twisted Tale of Amanda Knox Online

Created by K.J. Steinberg (‘This Is Us’), new series stars Grace Van Patten (’Under the Silver Lake’) as Knox, as well as Giuseppe De Domenico (‘Vermiglio’), Francesco Acquaroli (‘Dogman’), Roberta Mattei (‘Italian Race’), John Hoogenakker (‘G20’) and Sharon Horgan (‘Game Night’).

Grace Van Patten stars in 'The Twisted Tale of Amanda Knox'.

Moviefone recently had the pleasure of speaking with Grace Van Patten about her work on 'The Twisted Tale of Amanda Knox', her approach to playing the character, and what audiences will learn about the shocking true story.

You can read the full interview below or click on the video player above to watch our interviews with Van Patten, Giuseppe De Domenico, John Hoogenakker, K.J. Steinberg, and executive producer Warren Littlefield.

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Grace Van Patten in 'The Twisted Tale of Amanda Knox'. Photo: Hulu.

Moviefone: To begin with, can you talk about your approach to playing a character like Amanda Knox, who the world thinks that they already know everything about, and what will audiences learn about her from this series?

Grace Van Patten: I'm curious to see how people react. I think the show gives everyone an opportunity to form an opinion based on facts and what really happened as opposed to the press at the time and all these shocking headlines. I'm guilty of it too. I thought I knew a lot more than what I did, and working on it, I learned so much and I was shocked by the information. So, I think people watching it will feel the same way.

Grace Van Patten in 'The Twisted Tale of Amanda Knox'. Photo: Hulu.

MF: Finally, what did it mean to you personally to play this role and tell Amanda’s story?

GVP: Amanda's such a unique individual person and that's why these people who didn't understand that behavior thought it was so wrong. So, it was a fine line of trying to show her individual personality and show that it wasn't this wrong behavior that everyone took it as. She was just a 20-year-old girl who had never dealt with anything even close to this. I think it just shows that something like that could really happen to anyone and who knows how anyone would react to a situation like that, especially at such a young age.

Editorial Note: Krisily Fernstrom conducted this interview and contributed to this article.

(L to R) Stefano Cassetti and Grace Van Patten in 'The Twisted Tale of Amanda Knox'. Photo: Hulu.

What is the plot of ‘'The Twisted Tale of Amanda Knox'?

Amanda Knox (Grace Van Patten) arrives in Italy for her study abroad only to be wrongfully imprisoned for murder weeks later. Follow Knox's relentless fight to prove her innocence and reclaim her freedom and examines why authorities and the world stood so firmly in judgment.