We don't know what the episode is or what character he'll play, but if it keeps with the '60s original, the options range from an alien who's been hiding his third all eye all these years to a sadsack hired Santa who suddenly finds himself with a real magical gift bag.
Already announced for the show's premiere is guest star Adam Scott, who'll be putting a new spin on the classic "Nightmare At 30,000 Feet."
Steven Yeun and Greg Kinnear will appear in an episode called "The Traveler." There's no ep from the '60s series (or the '80s reboot) with that title, so it might be an original.
Other stars set to appear in the sci-fi series include Kumail Nanjiani, John Cho, Ike Barinholtz, Taissa Farmiga, Ginnifer Goodwin, Luke Kirby, Sanaa Lathan, Rhea Seehorn, Alison Tolman, Jacob Tremblay, Jessica Williams, and DeWanda Wise.
Rogen was a hilarious Victor Frankenstein in a recent episode of "Drunk History" and costarred in pal James Franco's "The Disaster Artist." His political comedy "Long Shot" with Charlize Theron opens May 3.
He also joins Yuen and Mark Hamill in the upcoming superhero series "Invincible."
You can stream all episodes of the original "Twilight Zone" on CBS All Access right now, which is also where the new series will air.