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Dec 20, 2018 - The "Big Sick" writers and director explain how the movie delivers universal appeal while telling a very specific story. "The Big Sick," starring Kumail Nanjiani, Zoe Kazan, Holly Hunter, Ray Romano, Anupam Kher, Zenobia Shroff, Adeel Akhtar, and Bo Burnham, and directed by Michael Showalter, is in theaters now.