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Samantha Who? (2007)

Christina Applegate as "Samantha"

Samantha Newly, the young vice president of a real-estate firm, is forced to start life over after a horrific hit-and-run accident leaves her with amnesia. As she reconnects with acquaintances in her old life, however, Sam is disconcerted to discover that she apparently was a self-centered, narcissistic witch with no successful relationships to speak of. But she wants to be good now, so she sets out to make amends with friends and family, including off-again, on-again girlfriend to roommate and ex-boyfriend Todd.

Screen Actors Guild Awards (2010) Nominated Outstanding Performance by a Female Actor in a Comedy Series
Emmy (Primetime) (2009) Nominated Outstanding Lead Actress in a Comedy Series
Golden Globe (2009) Nominated Best Performance by an Actress in a Television Series - Musical or Comedy
Screen Actors Guild Awards (2009) Nominated Outstanding Performance by a Female Actor in a Comedy Series
Emmy (Primetime) (2008) Nominated Outstanding Supporting Actress in a Comedy Series
Golden Globe (2008) Nominated Best Performance by an Actress in a Television Series - Musical or Comedy
Screen Actors Guild Awards (2008) Nominated Outstanding Performance by a Female Actor in a Comedy Series

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