Hoffman won his second Best Actor Oscar for his performance as the endearing but rule-bound Raymond Babbit, an autistic savant who can memorize phone books and is, of course, "an excellent driver." One of Hollywood's favorites since the '60s, he was Oscar-nominated again for 1997's "Wag the Dog." Since then, he's played Ben Stiller's dad in "Meet the Fockers," voiced Master Shifu in "Kung Fu Panda," and directed his first film, "Quartet." In 2014, he'll costar with Jon Favreau in "Chef."
After 1986's "Top Gun," Cruise was one of the biggest stars in Hollywood and the perfect guy to play impatient hot-shot Charlie in "Rain Man." The next year, Cruise went even more serious with "Born on the Fourth of July," for which he received his first Oscar nomination. He continued strong in the '90s with "A Few Good Men" and "Jerry Maguire," then launched his lucrative and long-running "Mission: Impossible" series. His next film is "Edge of Tomorrow" and there are plans for him to return as Jack Reacher.
Levinson won Best Director for "Rain Man," which still remains his biggest commercial hit. (Yes, that's him as the doctor at the final hearing.) Over the years, he's had hits ("Bugsy," Wag the Dog," "Good Morning, Vietnam") and misses ("Toys," "Sphere"). He was attached to the biopic "Gotti," but will now direct the Whitey Bulger film "Black Mass" instead.
The Italian-born actress moved to Los Angeles in 1988 and that same year landed roles in "Big Top Pee Wee," and "Rain Man," as the girlfriend of Tom Cruise, still one of her best-known roles. She also appeared in both "Hot Shots!" movies and narrowly lost out on the leads in "Pretty Woman" and "Flatliners" to Julia Roberts. In 2013, she directed her first feature film, "Miele," which screened at Cannes. She most recently starred in the Italian TV series "In Treatment."
Molen is primarily a producer, having worked on several of Steven Spielberg's films, including "Jurassic Park" and "Minority Report." He has only six acting credits to his name, including this film, as the doctor who's in charge of Raymond's money and custody.
Before playing Vern, Charlie's kindly caregiver, Roberts starred as Rooster on the '70s series "Baretta." He's guest starred on TV series from "MacGyver" to "Seinfeld," and most recently starred on "The First Family" series as Bernard.
Her role as Sally Dibbs, the waitress whose phone number Raymond recites from memory, was her first film part. Her other films include "Only You," "Beethoven," and "Jumanji," and she re-teamed with Cruise for "Jerry Maguire." She's also hosted her own daytime talk show, and wrote and directed the 2000 romantic comedy "Return to Me." She's become a Pixar regular, voicing characters in "Monsters University" and the "Toy Story" films.
Jenny had the small but memorable role of Iris, the "very sparkly" hooker who tries to pick up Raymond in Vegas. She also appeared in "Wired," "Thelma & Louse," "Leaving Las Vegas," "G.I. Jane," and (with Hoffman again) "Mad City." She guest starred on "The Shield," "24," and in "Battlestar Galactica" as the late wife of Admiral Adama. She received an Independent Spirit award nomination for the 1992 film "American Heart."
Robillard plays the small-town doctor who Charlie takes Raymond to, the one who first suggests Raymond has savant abilities. He's continued acting steadily, appearing in "Breakdown," "Terminator 3: Rise of the Machines," and, most recently, as Sal Nutter in the TV series "Hart of Dixie."