63
About
Mollie and James are together and raising a family, which now consists of an older Mikey and his baby sister, Julie. Tension between the siblings arises, and as well with Mollie and James when Mollie's brother Stuart moves in. Mikey is also learning how to use the toilet for the first time.
Theatrical
Dec 14, 1990
Box Office
$120.9M
Budget
$12.0M
Return
10.1x
DVD / Blu-ray
Oct 10, 2000
Director
Producer
Music
Studio
TriStar Pictures, Big Mouth Productions
Where to Watch
Region
Apple TV Store
Rent from
HD
$3.99
Apple TV Store
Buy from
HD
$12.99
Amazon Video
Rent from
HD
$3.99
Amazon Video
Buy from
HD
$14.99
Sony Pictures Core Amazon Channel
Stream included
HD
Included
See all 11 options →
Prices last updated October 1, 2026. Pricing and availability may vary by region.
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Cast
Full credits →J
John Travolta
James
K
Kirstie Alley
Mollie
O
Olympia Dukakis
Rosie
E
Elias Koteas
Stuart
T
Twink Caplan
Rona
B
Bruce Willis
Mikey (voice)
R
Roseanne Barr
Julie (voice)
D
Damon Wayans
Eddie (voice)
G
Gilbert Gottfried
Joey
M
Mel Brooks
Mr. Toilet Man (voice)
N
Neal Israel
Mr. Ross
L
Lesley Ewen
Debbie
N
Noelle Parker
Woman Client
D
Douglas Warhit
Man Client
T
Terry David Mulligan
IRS Inspector
P
Paul Shaffer
Taxi Businessman
D
Don S. Davis
Dr. Fleischer
M
Morris Panych
Arrogant Businessman
A
Alex Bruhanski
Needle Doctor
D
Dorothy Fehr
Blonde
Look Who's Talking Collection
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Quotes
See all →Humorous Reflection on Unusual Situations
Julie
Don't you just hate it when you get your head stuck in your placenta?
Quotes sourced from Wikiquote (© Wikiquote contributors), licensed under CC BY-SA 4.0. Modified for formatting/length.
Children's Innocence and Parental Humor
Mollie Ubriacco
Mommy is a girl, so I don't have a penis.
James Ubriacco
But she's got some set of balls.
Mollie Ubriacco
But Daddy is a big...
Quotes sourced from Wikiquote (© Wikiquote contributors), licensed under CC BY-SA 4.0. Modified for formatting/length.
